Quantifying mitral regurgitation at Aswan Heart Centre with AI-driven Auto CFQ

Robust and AI-driven, Auto CFQ circumvents the problems of other quantification methods to create a precise assessment of mitral valve regurgitation, regardless of orifice shape and size.

According to Dr. Mahmoud-Elsayed, while the 2D proximal isovelocity surface area (PISA) method of measuring regurgitation is widely used, it has inherent problems that affect its accuracy. “One of the main problems that the 2D PISA method faces is that it cannot validate multiple jets,” he noted. “It also assumes a circular orifice. And we know that many mitral regurgitation patients do not have a circular orifice; it is sometimes oval and sometimes a bizarre shape.” Dr. Mahmoud-Elsayed added that a second measurement method, 3D Vena Contracta Area, can measure non-circular orifices, but does not respect the duration of mitral regurgitation, which can occur throughout the systolic cycle and is irregular and dynamic. In contrast, 3D CFQ can measure orifices of any shape and takes the duration of the mitral regurgitation into account when quantifying flow volume.

3D CFQ uses a pinhole method, dividing the orifice into multiple small holes and measuring flow through each before adding them together to quantify the total flow. Dr. Mahmoud-Elsayed stated, “At last, now we have a tool that respects the duration of mitral regurgitation, respects the number of orifices and respects the morphology of the mitral regurgitation.”